Publications

BORDAY C., Chatonnet F., Thoby-Brisson M., Champagnat J., Fortin G. Neural tube patterning by Krox20 and emergence of a respiratory control. Respiratory Physiology & Neurobiology 2005, 149, 63-72.

BOUDINOT E., Taysse L. , Daulon S., Chatonnet A., Champagnat J. Foutz A.S. Effects of acetylcholinesterase and butyrylcholinesterase inhibition on breathing in mice adapted or not to reduced acetylcholinesterase. Pharmacology, Biochemistry and Behavior 2005, 80, 53-61.

THOBY BRISSON Muriel, Trinh Jean Baptiste, Champagnat Jean, Fortin Gilles. Emergence of the pre-Bötzinger respiratory rhythm generator in the mouse embryo. Journal of Neuroscience, 2005, 25 p.4307-4318.

SILVA-BARRAT S., Velluti J., Szente M., Batini C., Champagnat J. Exaggeration of epileptic-like patterns by nicotine receptor activation during the GABA withdrawal syndrome. Brain Research , 2005, 1042 p 133-143.

PASCUAL O., Traiffort E., Baker D.P., Galdes A., Ruat M., Champagnat J. Sonic Hedgehog signalling in Neurons of Adult Ventrolateral Nucleus Tractus Solitarius, European Journal of Neuroscience, 2005, 22 :389-96.


PASCUAL O., Roux J.C., Soulage C, Morin-Surun M.-P., Denavit-Saubié M., Péquignot J.M. Carotid chemodenervation approach to study oxygen sensing in brain stem catecholaminergic cells. Methods Enzymol. 381, p. 422-49, 2004.


COUTINHO A, Borday C., Gilthorpe J., Jungbluth S., Champagnat J., Lumsden A., Fortin G. Induction of a Para-facial rhythm generator by rhombomere 3 in the chick embryo. Journal of Neurosciences, Accepted (2004)

CHATONNET F., Boudinot E., Chatonnet E.A. Champagnat J., Foutz A.S. Breathing without acetylcholinesterase. Adv. Exp. Med. Biol; in press.


BORDAY C., Abadie V., Coutinho A., Germon I., Champagnat J., Fortin G. Pre-/post-otic rhombomeric interactions control the emergence of a respiratory-like rhythm generator in the mouse embryo. Journal of Neurosciences, Submitted (2004)

BORDAY C., Wrobel L., Fortin G., Champagnat J., Thaëron-Antono C., Thoby-Brisson M. Developmental gene control of brainstem function : views from the embryo. Progress in Biophysics and Molecular Biology. Vol.84, p.89-106.


Boudinot E, Emery M.J., Mouisel E., Chatonnet A., Champagnat J., Escourrou P., Foutz, A.S. Increased ventilation and CO2 chemosensitivity in acetylcholinesterase knockout mice. Resp. Physiol. Neurobiol., 140, p231-241.(2004).


Boudinot E, Yamada M, Wess J, Champagnat J, Foutz, AS Ventilatory pattern and chemosensitivity in M1 and M3 muscarinic receptor knockout mice, Resp. Physiol. Neurobiol., 139, p237-245.(2004).


THOBY BRISSON Muriel, Cauli B., Champagnat J., Fortin, G., Katz D. Expression of functional tyrosine kinase B receptors by rhythmically active respiratory neurons in the Pre-Bötzinger complex of neonatal mice. Journal of Neurosciences,2003, 23 : 7685-7689.


PRABHAKAR N., Champagnat J. Functional genomics and proteomics in control of breathing. Respir. Physiol. Neurobiol. 2003, 135 : 107-8.


CHATONNET F., Boudinot E., Chatonnet A., Taysse L., Daulon S., Champagnat J., Foutz A.S. Respiratory survival mechanisms in acetylcholinesterase knockout mouse. European Journal of Neuroscience, 18 : 1419-1427, 2003


CHATONNET Fabrice, Dominguez del Toro E., Thoby Brisson M., Champagnat J., Fortin G., Rijli Filipo, Antono-Thaëron C. From hindbrain segmentation to breathing after birth : developmental patterning in rhombomeres 3 and 4. Molecular Neurobiology, Vol 28, p.277-293 , 2003.


CHAMPAGNAT Jean, Denavit-Saubié M., Fortin G., Foutz A.S., Thaëron-Antono C., Thoby-Brisson M., Emergence of neural net function during brain development, J.Physiol ; Paris, 97, 1-3.


CHAMPAGNAT Jean, What is eupnea ? Respiratory Physiology & Neurobiology, 139, 91-95, 2003


BORDAY Caroline, Abadie V, Chatonnet F, Thoby-Brisson M, Champagnat J and Fortin G. Developmental molecular switches regulating breathing patterns in CNS. Respiratory Physiology & Neurobiology, Vol.135, p.121-132, 2003.


PASCUAL O., Morin-Surun M.-P., Barna B., Denavit-Saubié M., Péquignot J.-M., Champagnat J. Progesterone reverses the neuronal responses to hypoxia in rat nucleus tractus solitarius in vitro. J. Physiol  (London) 544.2. p.511-520 - 2002.


JUNGBLUTH S., Willecke K. , Champagnat J. Segment-specific expression of connexin 31 in the embryonic hindbrain is regulated by Krox20. Developmental Dynamics. 223 : 544-551 (2002).


CHATONNET F., Thoby-Brisson M., Abadie V., Dominguez del Toro E., Champagnat J. and Fortin G. Early development of respiratory rhythm generation in mouse and chick. Respir. Physiol & Neurobiology. 2002, 131, p.5-13.

CHATONNET F., Dominguez del Toro E., Voiculescu O., Charnay P. , Champagnat J. Different respiratory control systems are affected in homozygous and heterozygous Kreisler mutant mice. Eur. J. of Neurosci.,2002, Vol. 15, p684-692.


BOUDINOT E., Tremblay P., Champagnat J. Foutz A.S.Respiratory function in mice lacking or everexpressing the prion protein. Neuroscience Lett. 2002, 323, p. 89-92.


SZENTE M, Menini C , Velluti J.C., Champagnat J , Silvat-Barrat C. Muscarinic depression of synaptic transmission in the epileptogenic gaba withdrawal syndrome focus. J. Neurophysiological. 85 (5) : 2159-65. 2001.


MORIN-SURUN M.-P., Boudinot E, Dubois C., Matthes H.W., Kieffer B.L., Denavit-Saubié M., Champagnat J., Foutz A.S. Respiratory function in adult mice lacking the µ-opioid receptor : role of the d-receptors.Eur. J. Neurosci., vol.13, issue 9, p 1703. 2001.


PASCUAL O., Denavit-Saubié M., Dumas S., Kietzmann T., Ghilini G., Mallet J. and Pequignot J.M. Selective cardiorespiratory and catecholaminergic areas express the hypoxia-inducible factor-1 a (HIF-1a) under in vivo hypoxia in rat brainstem. Eur. J. of Neurosci. – Vol 14 – p1981-1991 – 2001.


DOMINGUEZ-DEL-TORO E., Borday V., Davenne M., Neun R., Rijli F., Champagnat J.Generation of a novel functional neuronal circuit in Hoxa1 mutant mice.J. of Neuroscience,  21 (15) : 5637-42. 2001.


BOUDINOT E., Morin-Surun M-P., Foutz A., Fournié-Zaluski M., Roques BP., Denavit-Saubié M. Effects of the potent analgesic enkephalin-catabolizing enzyme inhibitors RB 101 and kelatorphan on respiration.Pain, 90 : 7-13. 2001.


ROUX J.-C., Pequignot J.-M., Dumas S., Pascual O., Ghilini G., Pequignot J., Mallet J., Denavit-Saubié M.O2-sensing after carotid chemodenervation : hypoxic ventilatory responsiveness and upregulation of tyrosine hydroxylase mRNA in brainstem catecholaminergic cells. Eur. J. of Neurosci., Vol.12, p 3181-3190, 2000.


SILVA-BARRAT, C., J. Champagnat, Menini C.“The GABA-withdrawal syndrome: a model of local status epilepticus.”Neural Plasticity 7: 9-18. 2000.


POON  Chi-Sang, Zhou Zhongen, Champagnat J. NMDA receptor activity in utero averts respiratory depression and anomalous long-term depresion in newborn mice.J. of Neurosci., Vol. 20, p.1-6. 2000.


FORTIN G., Dominguez Del Toro E., Abadie V., Guimaraes L., Foutz A., Denavit-Saubié M., Rouyer F., Champagnat J.Genetic and developmental models for the neural control of breathing in vertebrates.J. Respiration Physiology 122 . 247-257. 2000.


ABADIE, V., J. Champagnat, Fortin G.“Branchiomotor activities in mouse embryo.”Neuro Report.11 : 141-145. 2000


MORIN-SURUN, M., Collin T, Denavit-Saubié M, Baulieu EE, Monnet FP . “Intracellular sigma-1 receptor modulates phospholipase C and protein kinase activities in the brainstem.”Proceedings of the National Academy of Science U.S.A. 96: 8196-8199. 1999.


JACQUIN, T., Sadoc G., Borday , V., Champagnat , J. “Pontine and medullary control of the respiratory activity in the trigeminal and facial nerves in the newborn mouse : an in vitro study.”Eur. J. of Neurosci. 11: 213-222.(1999).


FORTIN, G.,  Jungbluth, S., Lumsden, A, Champagnat , J.“Segmental specification of GABAergic inhibition during development of hindbrain neural networks.”Nature Neuroscience  2: 873-877. (1999).


ABADIE, V.,  Champagnat J, Fortin G, Couly G. “Succion-déglutition-ventilation et gènes du développement du tronc cérébral.”Archives de Pédiatrie 6: 1043-1047. (1999).


BORDAY, V., A. S. FOUTZ, et al. (1998). “Respiratory effects of glutamate receptor antagonists in neonate and adult mammals.” Eur.J.Pharmacol. 348: 235-246    


ZHOU, Z., J. CHAMPAGNAT, et al. (1997). “Phasic and long-term depression in brainstem nucleus tractus solitarius neurons: differing roles of AMPA receptor desensitization.” J.Neurosci. 17: 5349-5356.


DENAVIT-SAUBIE, M., J. CHAMPAGNAT, et al. (1997). “Maturation of brainstem respiratory neuronal networks.” Pediatric Pulmonology Suppl. 16: 216-217.


CHAMPAGNAT, J. and G. FORTIN (1997). “Primordial respiratory-like rhythm generation in the vertebrate embryo.” Trends Neurosci. 20(3): 119-124.


BORDAY, V. (1997). “A ventral pontine pathway promotes rhythmic activity in the medulla of neonate mice.” NeuroReport 8: 3679-3683.    


BORDAY, V., G. FORTIN, et al. (1997). “Early ontogeny of rhythm generation and control of breathing.” Respir.Physiol. 110: 245-249.


SCHMID, K., A. S. FOUTZ, et al. (1996). “Inhibitions mediated by glycine and GABA A receptors shape the discharge pattern of bulbar respiratory neurons.” Brain Research 710: 150-160.


REKLING, J. C., J. CHAMPAGNAT, et al. (1996). “Electroresponsive properties and membrane potential trajectories of three types of inspiratory neurons in the newborn mouse brain stem in vitro.” Journal of Neurophysiology 75(2): 795-810.


REKLING, J. C., J. CHAMPAGNAT, et al. (1996). “Thyrotropin-releasing hormone (TRH) depolarizes a subset of inspiratory neurons in the newborn mouse brain stem in vitro.” Journal of Neurophysiology 75(2): 811-819.       


McLEAN, H. A., J. CHAMPAGNAT, et al. (1996). “A cholecystokinin-B receptor antagonist potentiates GABAergic and glycinergic inhibition in the nucleus of the solitary tract of the rat.” European journal of neuroscience 8: 1078-1084.          
   

RICHE, D., A. S. FOUTZ, et al. (1995). “Developmental changes of NADPH-diaphorase neurons in the forebrain of neonatal and adult cat.” Developmental Brain Research 89: 139-145.


PIERREFICHE, O., J. CHAMPAGNAT, et al. (1995). “Calcium-dependent conductances control neurones  involved in termination of inspiration in cats.” Neuroscience Letters 184: 101-104.


PIERARD, C., J. CHAMPAGNAT, et al. (1995). “Brain stem energy metabolism response to acute hypoxia in anaesthetized rats: a 31P NMR study.” NeuroReport 7: 281-285. 


MORIN-SURUN, M. P., E. BOUDINOT, et al. (1995). “Involvement of NMDA receptors in the respiratory  phase transition is different in the adult guinea pig in  vivo and in the isolated brain stem preparation.” Journal of Neurophysiology 74(2): 770-778.            


MORIN-SURUN, M. P., E. BOUDINOT, et al. (1995). “Localization of chemosensitive structures in the isolated brainstem of adult guinea-pig.” Journal of Physiology 485(1): 203-212.



CASSUS-SOULANIS, S., A. S. FOUTZ, et al. (1995). “Involvement of NMDA receptors in inspiratory  termination in rodents: effects of wakefulness.” Brain Research 679: 25-33.       


BIANCHI, A. L., M. DENAVIT-SAUBIE, et al. (1995). “Central control of breathing in mammals: neuronal  circuitry, membrane properties, and neurotransmitters.” Physiological Reviews 75(1): 1-45.