|Affiliated doctoral schools|
Study in a comparative (« evo-devo ») perspective the morphogenesis of the central nervous system (CNS) and associated organs. We focus on two main themes: 1 – the control of cell proliferation in the fish (teleost) brain, and 2 – the evolution of peptidergic systems in chordates and the regulation of homeobox genes transcription in CNS-associated organs, in an ascidian model.
Our team’ research is focused on a comparative (“evo-devo”) approach of the central nervous system morphogenesis in two chordate models: a teleost fish, the medaka (Oryzias latipes) and an urochordate, the ascidian (Ciona intestinalis, Ciona savignyi).
-In the medaka, we study the control of cell proliferation, both in neural progenitors and in neural stem cells.
- In the ascidian, we study the evolution of peptidergic systems, and the regulation of transcription, for homeobox genes expressed in a CNS-associated organ.